The Menopause Brain by Dr. Lisa Mosconi

Dr. Lisa Mosconi’s The Menopause Brain is a groundbreaking, deeply reassuring, and empowering exploration of what happens to the female brain during the menopause transition. Backed by decades of neuroscience research, this book brings clarity to a life stage often misunderstood or misrepresented—even in the medical world.

Mosconi explains that menopause isn’t just about hot flashes and hormone shifts—it’s a neuroendocrine transition that reshapes the brain. Using accessible language, real stories, and brain imaging science, she unpacks how estrogen affects cognition, mood, memory, and sleep—and how the brain adapts and evolves in response.

What makes this book stand out is its compassionate blend of science and humanity. It doesn’t pathologize menopause; it reframes it as a natural and powerful transformation. Mosconi also provides evidence-based lifestyle strategies to support cognitive health through this period, including nutrition, exercise, sleep, and mental stimulation.

As a reader who’s passionate about health and aging well, I found The Menopause Brain to be both intellectually enriching and emotionally affirming. It’s the kind of book that replaces fear with understanding—and confusion with confidence.